Verapamil Calan Isoptin
Bolus doses are administered by direct IV injection over a minimum of 2 minutes.

Mix 100mg in 250 ml D5W.
Concentration 0.4mg per ml.

Initial 0.075-0.15 mg/kg over 3 minutes if needed administer second dose of 0.15 mg/kg in 15-30 minutes.
Maintenance: 1-10 mg/ht infusion.

Action: Calcium channel blockers-direct negative chronotropic & negative inotropic

Use: Acute and preventive treatment of PSVTs, and slowing ventricular response in atrial flutter and fibrillation

Verapamil: 2.5-5mg IV bolus over 2 min; repeat dose 5-10mg in 15-30 min then 5mg q 15 until desired response or total dose of 30mg given

Reduce oxygen demand; decreased SVR caused by vasodilatation of vascular smooth muscle (coronary vasodilation)
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