Nurse Bob's MICU/CCU Survival Guide
Overdose and Drug Reactions
Heavy Metals Overdose
Chelation Therapy
I. Definition of Chelation Therapy
A. The administration of chelating
agents to
remove heavy metals
II. Heavy metal intoxication involves lead, arsenic or mercury.
III. Types of Chelating Agents - Usually used for heavy
1. DMSA -
Dimercaptosuccinic Acid Chelating
agents
2. DMPS - Dimerpanesulfonic
acid
3. ALA - alpha
lipoic acid
4. Alpha
lipoic acid
(ALA)
5.
Aminophenoxyethane-tetraacetic
acid (BAPTA)
6. Deferasirox
7. Deferiprone
8. Deferoxamine
9.
Calcium-disodium EDTA and DMSA are only
approved for the removal of lead by the Food and Drug